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HYPERTENSION (HIGH BLOOD PRESSURE)

HYPERTENSION  Hypertension is a very common disorder  particularly in past middle age..  Hypertension itself is not a disease, But a risk factor for cardiovascular mortality or mobility..  Hypertension is also known as (High Blood Pressure) .. Blood pressure is the force of  your blood pushing , against the wall of the artries..  The normal range of blood pressure is 120/80mmHg.. High Blood pressure or Hypertension is the condition, In which the blood vessels have persistently raised pressure .. Hypertension is a seriously mental health condition increased the risk of Stroke, brain, kidney and other problems ..  It is a major cause of premature death worldwide with upwards of 1 in 4 men and 1 in 5 women .. * What are the symptoms of hypertension   Dizziness   Highblood pressure   Nausea   Vomiting   Irregular heartbeat   Mental confusion *What causes Hypertension . High salt in you diet  .Family history of High blood pressure  .Stress  .Lack of physical exercise  .Excess us

Best medication and treatment of Malaria

What is malaria? 
Malaria is a disease caused by the plasmodium parasite,transmitted by the bite of infected mosquito ..
There are four species of (protozoal parasite Plasmodium)
'P. Falcipuram'   'P. Vivax' 
'P. ovale'      'P. malariae'

In india, the national malaria Eradication programe (NMEP)started in 1958,appears complete disappearance of the disease in 1960s to 0.1m cases in 1960..

The NMEP was renamed national antimalaria programme (NAMP) Which now is national vector bone disease control programme (NVBDCP) with a wider disease coverage..

What are the Symptoms of malaria ?
 . Fever 
 . Fatigue 
 . Nausea 
 . Vomiting 
 . Headache 
 .Sweating 
 .Shivering 

What are the Best Medicines for the treatment of malaria ?
.Artemisin 
.primaquine
.Chloroquine 
.Mefloquine
.Artemether
.Proguanil
.Antifolate


Anti-malarial therapy is given in the following forms -
(A) Casual prophylaxis 
The preerythrocytic phases(in liver
Which is thr cause of malaria infection and clinical attacks ,is the target for the purpose.
Primaquine is the casual prophylaxis for all species of malaria, but has not been used in mass programmes ,because of its toxic effects. 
Proguanil is a casual prophylatic ,primarily  p. F ,but is not used in ,because of its weak activitiy against liver stages of p. V.. 
(B) Suppreive prophylaxis -The schizontocides which supress the erythrocytic phase than attack of malaria fever can be used as prophylatic.. 

Best combination used in treatment of malaria -
(1)For uncomplicated malaria
A-Vivax (also ovale, malariae) malaria 
1-Chloroquine + Primaquine
2-quinine +Doxycyline 
B-Chloroquine sensitive falcipuram malaria
Chloroquine +Primaquine 
C-Chloroquine resistance falcipuram malaria 
Artesunate +Meflaquine

(2)For sever/complicated malaria 
Artemether
Artesunate
Quinine 
Arteether 

Uses and objective of antimalarial drug 
.Prevent clinical attacks of malaria 
.Treat clinical attacks of malaria (Clinical curative) 
.Completely eradicate the parasite from the patient body 
.Cutdown human-mosquito transmission (gemetocidal)  

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HYPERTENSION (HIGH BLOOD PRESSURE)

HYPERTENSION  Hypertension is a very common disorder  particularly in past middle age..  Hypertension itself is not a disease, But a risk factor for cardiovascular mortality or mobility..  Hypertension is also known as (High Blood Pressure) .. Blood pressure is the force of  your blood pushing , against the wall of the artries..  The normal range of blood pressure is 120/80mmHg.. High Blood pressure or Hypertension is the condition, In which the blood vessels have persistently raised pressure .. Hypertension is a seriously mental health condition increased the risk of Stroke, brain, kidney and other problems ..  It is a major cause of premature death worldwide with upwards of 1 in 4 men and 1 in 5 women .. * What are the symptoms of hypertension   Dizziness   Highblood pressure   Nausea   Vomiting   Irregular heartbeat   Mental confusion *What causes Hypertension . High salt in you diet  .Family history of High blood pressure  .Stress  .Lack of physical exercise  .Excess us

Drug for cough

Cough It is protective reflex,and its a sudden expulsion of respiratory secretion and foreign particles from air passage..  It mainly occurs due to the stimulation of mechano or chemoreceptor in throat and respiratory passage..  Demulscent ( Agent that   Reliving pain and inflammation) Pharyngeal demulscent soothe the throat and reduce afferent impulses from the inflammed /irritated pharyngeal mucosa, thus provide sympatominetic relief in dry cough arising from throat..  Expectorant (Mucokinetics)  Thses are the drugs believed to increase bronchiol secretion or reduce its viscosity fascilating its removal by coughing..  Mucolytics drugs  . Bromhexine .Ambroxol  Acetylcysteine  .Carbocisteine Anti-tussive  Act in the CNS raise the threshold of cough centre or act peripherally in the respiratory tract to reduce tussal impulses or both tissue actions..  Opoid antitusive  .Codeine .Ethylmorphine Non opoid antitusive  .Noscapine (Narcotine) .Dextromethomorphone  .Chlophrnidol 

Tuberculosis (TB)

Tuberculosis  Tuberculosis is a granulomatous(structure found during inflammation) chronic disease caused by the mycobacterium tuberculosis..  About 1/3rth of the world population with this disease.. In which 10-15% develop disease over life time..  India was the highest contributor with 2.2m cases in 2014.. In 2012,the government of india has declared TB to a notifiable disease,So that any doctor who treats a TB patients has to notify it to the government..  Medication used in tuberculosis  First line drugs   This drugs have high antitubercular efficacy as well as low toxicity are used routinely .. These are the most potent and tolerated best oral drugs  Example  . Isoniazid  .Ethambutol .pyrazinamide .Rifampin Second line drug   These drugs have either low antituberculae efficacy or higher toxicity or both and are used, when the first line drug cannot be used or to supplement them..  These are less effective and bacteriosattic /More toxic oral drug for resista