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HYPERTENSION (HIGH BLOOD PRESSURE)

HYPERTENSION  Hypertension is a very common disorder  particularly in past middle age..  Hypertension itself is not a disease, But a risk factor for cardiovascular mortality or mobility..  Hypertension is also known as (High Blood Pressure) .. Blood pressure is the force of  your blood pushing , against the wall of the artries..  The normal range of blood pressure is 120/80mmHg.. High Blood pressure or Hypertension is the condition, In which the blood vessels have persistently raised pressure .. Hypertension is a seriously mental health condition increased the risk of Stroke, brain, kidney and other problems ..  It is a major cause of premature death worldwide with upwards of 1 in 4 men and 1 in 5 women .. * What are the symptoms of hypertension   Dizziness   Highblood pressure   Nausea   Vomiting   Irregular heartbeat   Mental confusion *What causes Hypertension . High salt in you...
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Anti-anginal drugs (chest pain)

Angina (Ischemic angina) 
It is a chest pain caused by reduced blood flow to the heart ..
It is also called angina pectoris 
Angina pectoris 
It is a pain syndrome due to induction of an adverse oxygen supply/demand situation in a proportion of the myocardium..

Types of angina 
(1)-Classical angina(Stable angina)  -Attacks are predicatbly provoked by exercise, ,eating cotious ..when the increased energy demand is withdrwan.. 
(2)-Varient /Prinzmetal/Vasopastic angina
Attacks occur at rest during sleep and are unpredictables.. 
(3)-Unstable angina -Increase in duration and severity of attacks ,which may occur even during rest ..
Mostly due to rupture of an antheromatous plaque attacking platelets.

Classification of drugs -
.Terminate attacks -Nitrates 
.Used for chronic prophylaxis -other drugs 

 (1)-Nitrates 
 Nitrates dilate the veins more than artries, peripheral pooling of blood and decreased venus return (preload on heart reduced) end diastolic size and pressure reduced.
   Short acting nitrates -Glyceryl trinitrates 
   Long acting nitrates -Isosorbide 

(2)-Beta blockers
Reduced cardiac work and oxygen consumption as a consequences decrease in heart rate.. 
EX -propanalol, Metoprolol

(3)-Calcium channel blocker 
Interfere with calcium movement into the cell and slower the movement of calcium in the cell.. 
Ex-Verapamil, Diltiazem ,Amlodipine 

(4)-Potassium channel openers 
Regulate the movement of ion across the cell membrane ..
 Ex-Nicorandil

(5)Other antianginal drugs-Trimetazadine,        Ranolazine ,Dipyrmidole
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Anonymous said…
Great post!
September 2, 2020 at 2:06 AM
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